Canadian Mouse Mutant Repository

Established in 2002 at The Hospital for Sick Children, the CMMR is a central repository for cryopreserved mouse ES cells, sperm, and embryos. The CMMR also archives somatic tissue from mouse models in a variety of formats (frozen, fixed, embedded, and glass-slide mounted) enabling worldwide access to specimens from established mouse models. Now located at the Toronto Centre for Phenogenomics, the CMMR provides fee-for-service access to its range of services and the publicly available mouse lines and ES cells in its repository.

Our objectives are to:

  • Cryopreserve the mouse resources of the large-scale mouse production projects at TCP to enable public distribution;
  • Provide cryopreservation and cryorecovery services to individual scientists;
  • Contribute to mouse cryobiology research & development; and
  • Establish best practices and operate in coordination with other repositories worldwide.

Archiving your mouse lines and samples generated from your mice allow:

  • Reduced number of mutant lines maintained as live animals;
  • More space in your animal colony;
  • Protection against disastrous events;
  • Long-term secure and monitored storage of your archived samples; and
  • Easier distribution of mice or germplasm to collaborators and/or other scientists.

Our services are detailed at the TCP website and include:

  • Embryo cryopreservation and recovery;
  • Sperm cryopreservation and recovery;
  • Strain services, including rederivation by IVF, speed expansion and strain rescue;
  • NorCOMM ES cell withdrawal; and
  • Cryostorage of cells, tissues, embryos and sperm.

Information about placing online requests and general service terms are below:

image of mouse in front of Helix